Whole Exome Sequencing Market Research Report 2027 Observational Studies with Key Vendors
Whole exome sequencing is a widely used next-generation
sequencing (NGS) method to determine the nucleotide sequence primarily of the
protein-coding regions of an individuals related sequences, representing
approximately 1% of the complete DNA sequence. The human exome represents less
than 2% of the genome but contains ~85% of known disease-related variants,
which makes it major usage in the identification and the determination of
genetic variants causing various diseases such as Miller syndrome and Alzheimer’s.
Global Whole
Exome Sequencing Market Size is estimated to be valued at USD 2,696.03
Million by 2025 and is expected to register a CAGR of 19.80% during the
forecast period.
Segment Analysis
The global whole exome sequencing market has been segmented
on the basis of product, technology, application, and end user. The market,
based on product, has been segmented into kits, sequencer, and services. Kits
are further segmented into DNA Fragmentation, End Repair, A-Tailing, And Size
Selection Kits, Library Preparation, and Target Enrichment. Services are
further sub-segmented into Sequencing Services, Data Analysis (Bioinformatics),
and Others. The global whole exome sequencing market, by technology, has been
categorized as Sequencing by Synthesis (SBS), ION Semiconductor Sequencing, and
others. The market by application is segmented into diagnostics, drug discovery
and development, agriculture and animal research, others. Based on end user,
the market is segmented into research centers and government institutes,
hospitals and diagnostics centers, pharmaceutical & biotechnology
companies, and others.
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Regional Analysis
The Americas was the largest market for whole exome
sequencing in 2019. The growth of the Americas market is due to the high
prevalence rate of cancer and other chronic disorders and rising healthcare
expenditure. Additionally, favorable initiatives by the government and other
organizations for the development and adoption of whole-exome sequencing
technologies are driving the market for whole-exome sequencing. For instance, in 2018, All of Us Research
Program, a part of the National Institutes of Health, awarded funds over USD
28.6 million to establish three genome centers in the US. These centers aim to
produce genome data for researchers and the program’s precision medicine
research platform, a national resource to support studies on a variety of
important health questions.
Europe is the second-largest market for whole exome
sequencing with Western Europe, holding the largest market share. The European
market is expected to register a sturdy growth rate during the forecast period
due to rising cases of cancer and increasing programs for the adoption of
genome sequencing. According to the International Agency for Research on
Cancer, in 2018, there were 4,229,662 cases of cancer in Europe. This
increasing number of cases of cancer and rising genome mapping programs are
expected to have a positive impact on the growth of the whole exome sequencing
market.
Asia-Pacific is expected to represent the highest market
growth potential over the forecast period due to the growing patient pool and
increasing technological advancements. The fast growth of the Asia-Pacific
region is due to the increasing per capita income along with government
initiatives to enhance the quality of healthcare and rising diabetes being the
major concern in this region. China, India, and Australia have a lucrative
market for whole exome sequencing due to the growing older population.
Moreover, according to the report published by the United Nations in 2015, the
number of older people aged 60 years or above in the world is predicted to grow
by 56% between 2015 and 2030. 66% of the older population out of the total
global population would also reside in the Asia-Pacific region.
In the Middle East & Africa, the whole exome sequencing
market is driven by increasing obesity issues, rising initiatives by
governments to improve patient care, and favorable reimbursement policies.
Key Players
Market Research Future (MRFR) Illumina Inc. (US), BGI (China), Eurofins Scientific
(Belgium), Thermo Fisher Scientific (US), Agilent Technologies, Inc. (US), F.
Hoffmann-La Roche Ltd (Switzerland), GENEWIZ (US), Ambry Genetics (US ),
Macrogen, Inc. (South Korea), Integragen SA (France), as the Key Players in the Global Whole Exome
Sequencing Market.
Key Findings of the Study
The Global Whole Exome Sequencing Market is projected to
reach over USD 2,696.03 Million by 2025 at a 80% CAGR during the review period
of 2019 to 2025.
The US held a market share of 87.55% in 2019. Initiatives of
major players and rising product launches are driving the market growth. For
instance, In January 2020, Illumina (US) announced the launch of NextSeq 1000
and NextSeq 2000 Sequencing Systems offering breakthrough system design,
chemistry innovations, and on-instrument integrated informatics for rapid
secondary analysis.
Based on product, the kits segment accounted for the largest
market share of 60.9% in 2019.
On the basis of end user, the hospitals & diagnostic
laboratory segment accounted for a significant market share of 33.4% in 2018.
Key manufacturers in the whole exome sequencing market, such
as Illumina Inc., Eurofins Scientific, Thermo Fisher Scientific, Agilent
Technologies, Inc. are adopting strategies such as geographic expansions,
corporate acquisitions, and product launches as growth strategies.
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Market Research Future
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